STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdA-2Prefoldin alpha subunit 2; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (146 aa)    
Predicted Functional Partners:
pfdB
Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
 0.995
CL1_0816
Chaperonin subunit beta; COG0459; Belongs to the TCP-1 chaperonin family.
   
 0.868
CL1_1989
Chaperonin subunit alpha; COG0459; Belongs to the TCP-1 chaperonin family.
   
 0.868
CL1_0006
Hypothetical protein containing prefoldin beta-like domain; COG0206.
   
 0.801
rpl18a
50S ribosomal protein LX; COG2157.
  
    0.774
rpl18e
Ribosomal protein L18e; COG1727; Belongs to the eukaryotic ribosomal protein eL18 family.
  
    0.769
rps17
30S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
    0.766
rpl31e
50S ribosomal protein L31e; COG2097; Belongs to the ribosomal protein L31e family.
 
    0.758
CL1_1582
Hypothetical protein; COG2118; Belongs to the PDCD5 family.
 
   0.757
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
  
    0.749
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.