STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1795UDP-glucose 4-epimerase; COG0451. (310 aa)    
Predicted Functional Partners:
CL1_0841
Putative UDP- or dTTP-glucose 4-epimerase or 4-6-dehydratase; COG0451.
 
  
 
0.916
CL1_0291
Sugar-phosphate nucleotidyltransferase 1; COG1208.
 
 0.901
CL1_0840
Sugar-phosphate nucleotidyltransferase 2; COG1208.
 
 0.896
CL1_0109
Putative sugar-phosphate nucleotidyltransferase; COG1208.
 
 0.894
CL1_0414
Putative mannose-1-phosphate guanylyltransferase; COG1208.
 
 0.890
rps3
30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 0.863
CL1_0469
Bifunctional mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; COG0836; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.846
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.846
rps28e
30S ribosomal protein S28e; COG2053; Belongs to the eukaryotic ribosomal protein eS28 family.
   
 0.841
rps19p
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 0.838
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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