STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1807Biotin-protein ligase; COG0340. (237 aa)    
Predicted Functional Partners:
CL1_0654
methylmalonyl-CoA decarboxylase subunit alpha; COG4799.
 
 
 0.999
CL1_1335
Hypothetical protein; COG2516.
     
  0.900
CL1_0656
Putative methylmalonyl-CoA decarboxylase subunit gamma; COG0511.
 
 
 
 0.886
CL1_1697
Putative biotin biosynthesis protein BioY; COG1268.
 
   
 0.800
rnj
Hypothetical protein containing metallo-beta-lactamase superfamily; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
      0.653
CL1_1806
Fructose 1,6-bisphosphate aldolase; COG1830.
       0.641
CL1_1808
Proton/glutamate symporter; COG1301.
     
 0.638
CL1_1805
Pyruvate carboxylase subunit B; COG5016.
 
     0.633
CL1_1311
2-amino-3-ketobutyrate coenzyme A ligase; COG0156.
  
  
 0.584
nadE
Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.573
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.