STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1815CRISPR-associated protein Cas5; COG1688. (227 aa)    
Predicted Functional Partners:
CL1_1816
CRISPR-associated autoregulator, DevR family 2; COG1857.
 
 
 0.984
CL1_1817
Hypothetical protein.
       0.901
CL1_1818
CRISPR-associated Cas6 family protein 2; COG1583.
 
   
 0.865
CL1_0377
CRISPR-associated autoregulator, DevR family 1; COG1857.
 
 
 0.757
CL1_0507
Glycosyl transferase family protein 6; COG1807.
  
     0.689
CL1_1964
Hypothetical protein; COG1672.
 
     0.675
CL1_0839
Putative oligosaccharyl transferase, STT3 subunit 1; COG1287.
  
   
 0.648
CL1_0376
CRISPR-associated CXXC_CXXC protein Cst1.
 
   
 0.625
CL1_1103
Hypothetical protein; COG0535.
  
     0.606
CL1_0375
CRISPR-associated Cas6 family protein 1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
 
   
 0.583
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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