STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1816CRISPR-associated autoregulator, DevR family 2; COG1857. (327 aa)    
Predicted Functional Partners:
CL1_1815
CRISPR-associated protein Cas5; COG1688.
 
 
 0.968
CL1_0378
CRISPR-associated protein Cas5, Tneap type; COG1688.
 
 
 0.885
CL1_0379
CRISPR-associated helicase Cas3; COG1203.
 
 
 0.859
CL1_1811
CRISPR-associated helicase Cas3 domain-containing protein; COG1203.
 
 
 0.845
CL1_1818
CRISPR-associated Cas6 family protein 2; COG1583.
 
   
 0.831
CL1_1817
Hypothetical protein.
       0.804
CL1_0376
CRISPR-associated CXXC_CXXC protein Cst1.
 
     0.720
CL1_0507
Glycosyl transferase family protein 6; COG1807.
  
     0.549
CL1_1812
CRISPR-associated Cas4 family protein 3; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.519
cas1-2
CRISPR-associated Cas1 family protein 1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.487
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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