Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_1818CRISPR-associated Cas6 family protein 2; COG1583. (237 aa)    
Predicted Functional Partners:
CL1_1815
CRISPR-associated protein Cas5; COG1688.
 
   
 0.865
CL1_1816
CRISPR-associated autoregulator, DevR family 2; COG1857.
 
   
 0.839
CL1_1817
Hypothetical protein.
       0.790
CL1_1956
CRISPR-associated RAMP protein, Csm4 family; COG1567.
 
   
 0.584
CL1_1313
Replication factor C small subunit; COG1372.
  
     0.578
CL1_1953
CRISPR-associated protein, Csm1 family; COG1353.
 
   
 0.554
CL1_0924
Hypothetical protein; COG0037.
 
     0.540
CL1_1957
CRISPR-associated RAMP protein, Csm5 family; COG1332.
 
     0.516
cas2
CRISPR associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.475
CL1_1955
CRISPR-associated RAMP protein, Csm3 family; COG1337.
 
   
 0.475
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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