Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
CL1_1851Cadmium-translocating P-type ATPase; COG2217. (695 aa)    
Predicted Functional Partners:
CL1_1850
Transcription regulator, ArsR family 9; COG0640.
 
  
 0.952
CL1_2038
Transcription regulator, AsnC family 5; COG1522.
     
 0.936
CL1_1898
Amino acid transporter; COG0531.
     
 0.822
CL1_0211
Glutaredoxin/thioredoxin-like protein; COG0526.
  
  
 0.688
CL1_1849
Hypothetical protein; COG0471.
     
 0.633
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
       0.626
CL1_0980
Putative cation efflux system protein; COG0053.
 
 
 0.530
CL1_1286
Hypothetical protein; COG1988.
      
 0.529
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
     
 0.494
CL1_1512
Molybdate/tungstate ABC transporter periplasmic substrate-binding protein; COG0725.
     
 0.490
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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