Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1862Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (215 aa)    
Predicted Functional Partners:
CL1_0385
Glutaredoxin-like protein 2; COG0526.
  
 0.783
CL1_0211
Glutaredoxin/thioredoxin-like protein; COG0526.
  
 0.765
CL1_0213
Glutaredoxin-like protein 1; COG0526.
  
 0.765
CL1_1863
Putative formate dehydrogenase; COG0243.
  
  
 0.759
CL1_1123
Thioredoxin reductase; COG0492.
  
 
 0.734
CL1_1996
Putative pyridine nucleotide-disulfide oxidoreductase; COG0492.
  
 
 0.734
CL1_1864
Hypothetical protein; COG1711.
       0.696
hflX
GTP-binding protein, HflX family; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
      0.666
CL1_1842
Rubrerythrin; COG1592.
  
  
 0.664
CL1_1841
Rubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
  
  
 0.643
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.