STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1870Aromatic amino acid permease; COG0814. (398 aa)    
Predicted Functional Partners:
cobB
NAD-dependent deacetylase; COG0846; Belongs to the sirtuin family. Class III subfamily.
     
 0.766
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.672
CL1_1872
Hypothetical protein.
       0.602
mfnA
Tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
    
 0.589
atpC
V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 0.541
CL1_0807
DNA helicase; COG1112.
  
 
 
 0.540
atpF
V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
  
  0.529
CL1_1898
Amino acid transporter; COG0531.
   
 
 0.506
CL1_1873
Hypothetical protein; COG1011.
       0.505
CL1_1874
Hypothetical protein; COG2411.
       0.505
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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