STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1885Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; COG0452. (405 aa)    
Predicted Functional Partners:
CL1_1361
Hypothetical protein; COG1701.
 
  
 0.961
CL1_1084
Phosphopantetheine adenylyltransferase; COG1019.
    
 0.911
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
   
 0.698
CL1_1886
Hypothetical protein; COG1993.
       0.671
crcB
Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.671
CL1_1884
Putative mechanosensitive channel; COG0668.
       0.639
CL1_1196
GHMP kinase 2; COG1829.
 
   
 0.629
CL1_1888
Sodium/hydrogen exchanger; COG0025.
   
 
 0.526
CL1_0582
Hypothetical protein; COG0639.
   
 
 0.523
CL1_0807
DNA helicase; COG1112.
   
 
 0.523
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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