Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_1895Putative peroxiredoxin, bacterioferritin comigratory protein; COG1225. (153 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase; COG0125.
   
   0.799
CL1_1896
Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family.
  
   0.743
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
  
    0.676
CL1_1836
Rubrerythrin-like protein 4; COG1633.
     
 0.666
CL1_1898
Amino acid transporter; COG0531.
     
 0.590
CL1_1862
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.523
CL1_1835
GNAT family acetyltransferase 3; COG0454.
  
    0.517
CL1_0862
Ribonucleoside-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.506
CL1_1897
Hypothetical protein; COG0568.
       0.483
CL1_1842
Rubrerythrin; COG1592.
     
 0.457
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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