STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_1942COG1409. (508 aa)    
Predicted Functional Partners:
CL1_1943
Hypothetical protein; COG0517.
       0.916
CL1_1944
Hypothetical protein; COG0121.
     
 0.874
CL1_1945
Restriction endonuclease, type I; COG2810.
 
     0.842
cpgS
Putative cyclic 2,3-diphosphoglycerate synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
 
     0.667
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.548
pgk2
Putative 2-phosphoglycerate kinase; COG2074.
 
     0.519
CL1_1126
RNA-binding protein containing THUMP domain; COG1818.
  
     0.512
CL1_0359
RNA binding protein containing KH domain; COG0195.
 
     0.476
CL1_0182
Hypothetical protein; COG1817.
  
     0.458
CL1_1346
Putative transcription regulator, penicillinase repressor family; COG3682.
  
     0.456
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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