Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CL1_1967Membrane-bound phosphoesterase; COG0671. (270 aa)    
Predicted Functional Partners:
CL1_1966
Hypothetical protein containing HAD-like domain 8; COG4087.
       0.838
CL1_1965
Hypothetical protein; COG1739.
     
 0.837
atpC
V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.619
rpl6
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.563
CL1_1601
Asparagine synthase; COG0367.
  
 
 0.524
CL1_0935
V-type ATP synthase subunit I; COG1269; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.507
atpF
V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.488
CL1_1964
Hypothetical protein; COG1672.
       0.482
CL1_1968
Hypothetical protein; COG0843.
       0.476
CL1_0748
Glycosyl transferase family 2 protein 2; COG0463.
  
  
 0.427
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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