| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CL1_1465 | CL1_1987 | CL1_1465 | CL1_1987 | Hypothetical protein; COG1617. | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | 0.826 |
| CL1_1465 | kae1 | CL1_1465 | CL1_1087 | Hypothetical protein; COG1617. | Putative DNA-binding/iron metalloprotein/AP endonuclease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.837 |
| CL1_1598 | CL1_1987 | CL1_1598 | CL1_1987 | Putative translation factor, sua5 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | 0.500 |
| CL1_1598 | kae1 | CL1_1598 | CL1_1087 | Putative translation factor, sua5 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative DNA-binding/iron metalloprotein/AP endonuclease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.805 |
| CL1_1598 | rsmA | CL1_1598 | CL1_0280 | Putative translation factor, sua5 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.498 |
| CL1_1987 | CL1_1465 | CL1_1987 | CL1_1465 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Hypothetical protein; COG1617. | 0.826 |
| CL1_1987 | CL1_1598 | CL1_1987 | CL1_1598 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Putative translation factor, sua5 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.500 |
| CL1_1987 | CL1_1988 | CL1_1987 | CL1_1988 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Hypothetical protein; COG0620. | 0.916 |
| CL1_1987 | CL1_1989 | CL1_1987 | CL1_1989 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Chaperonin subunit alpha; COG0459; Belongs to the TCP-1 chaperonin family. | 0.866 |
| CL1_1987 | fusA | CL1_1987 | CL1_1929 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.543 |
| CL1_1987 | htpX | CL1_1987 | CL1_1990 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Putative heat shock protein HtpX 1; COG0501; Belongs to the peptidase M48B family. | 0.716 |
| CL1_1987 | infB | CL1_1987 | CL1_1746 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.620 |
| CL1_1987 | kae1 | CL1_1987 | CL1_1087 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | Putative DNA-binding/iron metalloprotein/AP endonuclease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.989 |
| CL1_1987 | rps15 | CL1_1987 | CL1_0163 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | 30S ribosomal protein S15; COG0184. | 0.516 |
| CL1_1987 | rsmA | CL1_1987 | CL1_0280 | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. | 0.502 |
| CL1_1988 | CL1_1987 | CL1_1988 | CL1_1987 | Hypothetical protein; COG0620. | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | 0.916 |
| CL1_1988 | CL1_1989 | CL1_1988 | CL1_1989 | Hypothetical protein; COG0620. | Chaperonin subunit alpha; COG0459; Belongs to the TCP-1 chaperonin family. | 0.629 |
| CL1_1988 | htpX | CL1_1988 | CL1_1990 | Hypothetical protein; COG0620. | Putative heat shock protein HtpX 1; COG0501; Belongs to the peptidase M48B family. | 0.403 |
| CL1_1989 | CL1_1987 | CL1_1989 | CL1_1987 | Chaperonin subunit alpha; COG0459; Belongs to the TCP-1 chaperonin family. | Putative Mn2+-dependent serine/threonine protein kinase; COG3642. | 0.866 |
| CL1_1989 | CL1_1988 | CL1_1989 | CL1_1988 | Chaperonin subunit alpha; COG0459; Belongs to the TCP-1 chaperonin family. | Hypothetical protein; COG0620. | 0.629 |