| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CL1_1867 | dys | CL1_1867 | CL1_1999 | Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.602 |
| CL1_1867 | flpA | CL1_1867 | CL1_1402 | Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.754 |
| CL1_1867 | rpl10e | CL1_1867 | CL1_0631 | Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 50S ribosomal protein L10E; COG0197; Belongs to the universal ribosomal protein uL16 family. | 0.737 |
| CL1_1867 | rps13 | CL1_1867 | CL1_0596 | Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. | 0.461 |
| CL1_1867 | rps19e | CL1_1867 | CL1_1578 | Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.723 |
| CL1_1998 | dys | CL1_1998 | CL1_1999 | Glucose-1-dehydrogenase; COG1028. | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.635 |
| CL1_1998 | eif5a | CL1_1998 | CL1_0262 | Glucose-1-dehydrogenase; COG1028. | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.450 |
| dys | CL1_1867 | CL1_1999 | CL1_1867 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Transcription elongation factor S (TFS_arch); COG1594; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.602 |
| dys | CL1_1998 | CL1_1999 | CL1_1998 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Glucose-1-dehydrogenase; COG1028. | 0.635 |
| dys | eif5a | CL1_1999 | CL1_0262 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | 0.999 |
| dys | flpA | CL1_1999 | CL1_1402 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.712 |
| dys | pheS | CL1_1999 | CL1_0342 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | phenylalanyl-tRNA synthetase alpha subunit; COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.574 |
| dys | rpl10e | CL1_1999 | CL1_0631 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 50S ribosomal protein L10E; COG0197; Belongs to the universal ribosomal protein uL16 family. | 0.664 |
| dys | rps13 | CL1_1999 | CL1_0596 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. | 0.594 |
| dys | rps19e | CL1_1999 | CL1_1578 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.576 |
| dys | speE | CL1_1999 | CL1_1423 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. | 0.584 |
| dys | top6A | CL1_1999 | CL1_1917 | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.635 |
| eif5a | CL1_1998 | CL1_0262 | CL1_1998 | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Glucose-1-dehydrogenase; COG1028. | 0.450 |
| eif5a | dys | CL1_0262 | CL1_1999 | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Putative deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | 0.999 |
| eif5a | flpA | CL1_0262 | CL1_1402 | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.535 |