STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_2016Hypothetical protein; COG2266. (179 aa)    
Predicted Functional Partners:
cobS
Putative cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.961
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
  0.934
CL1_2015
Hypothetical protein.
       0.818
CL1_2020
Putative phosphatidylglycerophosphatase A; COG1267.
 
     0.661
CL1_2013
Hypothetical protein; COG2038; Belongs to the UPF0284 family.
 
     0.568
CL1_0839
Putative oligosaccharyl transferase, STT3 subunit 1; COG1287.
  
     0.537
CL1_1196
GHMP kinase 2; COG1829.
  
     0.530
CL1_1187
DNA-binding protein, Tfx type; COG1356.
  
     0.516
CL1_1332
Transcription regulator, AbrB/SpoV family; COG0704.
  
     0.512
CL1_0507
Glycosyl transferase family protein 6; COG1807.
  
     0.504
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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