STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANP27522.1Pfam: Thymidine kinase. (203 aa)    
Predicted Functional Partners:
dut
DUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
 0.972
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.934
ANP28098.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.932
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.931
ANP28097.1
Pfam: Pyrimidine nucleoside phosphorylase C-terminal domain; Pfam: Glycosyl transferase family, a/b domain; SMART: Pyrimidine nucleoside phosphorylase C-terminal domain; TIGRFAM: Y_phosphoryl: pyrimidine-nucleoside phosphorylase; Pfam: Glycosyl transferase family, helical bundle domain.
    
 0.928
ANP27383.1
TIGRFAM: deoD: purine nucleoside phosphorylase; Pfam: Phosphorylase superfamily.
  
 
 0.924
ANP28093.1
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.910
ANP26806.1
Hypothetical protein; Pfam: 5'-nucleotidase, C-terminal domain; PRINTS: Apyrase family signature; TIGRFAM: LPXTG_anchor: LPXTG cell wall anchor domain; Belongs to the 5'-nucleotidase family.
    
  0.902
ANP26948.1
Hypothetical protein; PRINTS: Apyrase family signature; Pfam: Calcineurin-like phosphoesterase; Pfam: 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
    
  0.902
ANP27320.1
TIGRFAM: PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component; TIGRFAM: PTBA: PTS system, glucose subfamily, IIA component; TIGRFAM: EIIB_glc: PTS system, glucose-like IIB component; Pfam: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; Pfam: phosphotransferase system, EIIB; Pfam: Phosphotransferase system, EIIC.
 
   
 0.817
Your Current Organism:
Dermabacter vaginalis
NCBI taxonomy Id: 1630135
Other names: D. vaginalis, DSM 100050, Dermabacter sp. AD1-86, Dermabacter vaginalis Chang et al. 2016, KCTC 39585, strain AD1-86
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