STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANP28145.1DNA polymerase III, alpha subunit; Pfam: PHP domain; Pfam: OB-fold nucleic acid binding domain; TIGRFAM: polc: DNA polymerase III, alpha subunit; Pfam: Bacterial DNA polymerase III alpha subunit; SMART: DNA polymerase alpha chain like domain; Pfam: Helix-hairpin-helix motif. (1185 aa)    
Predicted Functional Partners:
ANP26563.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.978
ANP27534.1
Pfam: DNA polymerase III, delta subunit; TIGRFAM: holA: DNA polymerase III, delta subunit.
  
 0.977
ANP28438.1
Pfam: DNA polymerase III, delta subunit; SMART: ATPases associated with a variety of cellular activities.
 
 0.970
ANP26927.1
Hypothetical protein; Pfam: Exonuclease.
   
 0.967
ANP26792.1
DNA polymerase III, subunit gamma and tau; SMART: ATPases associated with a variety of cellular activities; TIGRFAM: dnaX_nterm: DNA polymerase III, subunit gamma and tau; Pfam: DNA polymerase III, delta subunit; Pfam: DNA polymerase III subunits gamma and tau domain III.
  
 0.966
ANP27771.1
Exonuclease, DNA polymerase III, epsilon subunit; Pfam: Exonuclease; SMART: GIY-YIG type nucleases (URI domain); Pfam: GIY-YIG catalytic domain; TIGRFAM: dnaq: exonuclease, DNA polymerase III, epsilon subunit family.
    
 0.944
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 0.845
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
  
   
 0.797
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.773
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
    0.759
Your Current Organism:
Dermabacter vaginalis
NCBI taxonomy Id: 1630135
Other names: D. vaginalis, DSM 100050, Dermabacter sp. AD1-86, Dermabacter vaginalis Chang et al. 2016, KCTC 39585, strain AD1-86
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