STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANP28430.1Pfam: Protein of unknown function (DUF4244). (69 aa)    
Predicted Functional Partners:
ANP28429.1
Hypothetical protein; Pfam: Type II secretion system (T2SS), protein F.
 
   
 0.852
ANP28428.1
TIGRFAM: heli_sec_ATPase: helicase/secretion neighborhood ATPase; Pfam: Type II/IV secretion system protein.
     
 0.746
ANP28427.1
Hypothetical protein.
       0.692
ANP28431.1
Hypothetical protein.
       0.543
ANP28432.1
TIGRFAM: tadE_like_DECH: helicase/secretion neighborhood TadE-like protein.
       0.543
ANP26699.1
ModE molybdate transport repressor domain-containing protein; PRINTS: LysR bacterial regulatory protein HTH signature; Pfam: LysR substrate binding domain; Pfam: Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.449
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.407
Your Current Organism:
Dermabacter vaginalis
NCBI taxonomy Id: 1630135
Other names: D. vaginalis, DSM 100050, Dermabacter sp. AD1-86, Dermabacter vaginalis Chang et al. 2016, KCTC 39585, strain AD1-86
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