STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
atpCF-type h+-transporting atpase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane (114 aa)    
Predicted Functional Partners:
atpD
F-type h+/na+-transporting atpase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
  
 0.999
atpB
F-type h+-transporting atpase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane
  
 0.999
atpE
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
  
 0.999
atpA
F-type h+/na+-transporting atpase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
  
 0.999
atpH
F-type h+-transporting atpase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
  
 0.999
atpG
F-type h+-transporting atpase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
  
 0.999
WD_0429
F-type h+-transporting atpase subunit b; Belongs to the ATPase B chain family
  
 0.996
WD_0430
F-type h+-transporting atpase subunit b; Belongs to the ATPase B chain family
  
 0.996
nuoD
Nadh-quinone oxidoreductase subunit d; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
  
 
 0.938
nuoE
NADH dehydrogenase I, E subunit; Identified by similarity to EGAD:163269; match to PF01257 protein family HMM PF01257; match to TIGR01958 protein family HMM TIGR01958
  
 
 0.934
Your Current Organism:
Wolbachia sp. Dme
NCBI taxonomy Id: 163164
Other names: W. endosymbiont of Drosophila melanogaster, Wolbachia (endosymbiont of Drosophila melanogaster), Wolbachia endosymbiont of Drosophila melanogaster, Wolbachia pipientis wMel, Wolbachia sp. wMel
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