AMV16312.1 protein (Planctomyces sp. SHPL14)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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[Homology]

Score

AMV16312.1

Hypothetical protein. (495 aa)

Predicted Functional Partners:

AMV16313.1

0.924

AMV19427.1

0.792

AMV17645.1

0.775

AMV17649.1

0.775

AMV17698.1

0.775

AMV18679.1

0.775

AMV19109.1

0.775

AMV19713.1

0.775

AMV20516.1

0.775

AMV16790.1

0.774

Your Current Organism:

Planctomyces sp. SHPL14

NCBI taxonomy Id: 1632864
Other names: P. sp. SH-PL14, Planctomyces sp. SH-PL14

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMV16312.1	AMV16313.1	VT03_00380	VT03_00385	Hypothetical protein.	Planctomycete cytochrome C.	0.924
AMV16312.1	AMV16790.1	VT03_00380	VT03_02800	Hypothetical protein.	Planctomycete cytochrome C.	0.774
AMV16312.1	AMV17645.1	VT03_00380	VT03_07110	Hypothetical protein.	Planctomycete cytochrome C.	0.775
AMV16312.1	AMV17649.1	VT03_00380	VT03_07130	Hypothetical protein.	Planctomycete cytochrome C.	0.775
AMV16312.1	AMV17698.1	VT03_00380	VT03_07375	Hypothetical protein.	Planctomycete cytochrome C.	0.775
AMV16312.1	AMV18679.1	VT03_00380	VT03_12350	Hypothetical protein.	Planctomycete cytochrome C.	0.775
AMV16312.1	AMV19109.1	VT03_00380	VT03_14560	Hypothetical protein.	Planctomycete cytochrome C.	0.775
AMV16312.1	AMV19427.1	VT03_00380	VT03_16155	Hypothetical protein.	Planctomycete cytochrome C.	0.792
AMV16312.1	AMV19713.1	VT03_00380	VT03_17585	Hypothetical protein.	Planctomycete cytochrome C.	0.775
AMV16312.1	AMV20516.1	VT03_00380	VT03_21640	Hypothetical protein.	Planctomycete cytochrome C.	0.775
AMV16313.1	AMV16312.1	VT03_00385	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.924
AMV16790.1	AMV16312.1	VT03_02800	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.774
AMV17645.1	AMV16312.1	VT03_07110	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.775
AMV17649.1	AMV16312.1	VT03_07130	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.775
AMV17698.1	AMV16312.1	VT03_07375	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.775
AMV18679.1	AMV16312.1	VT03_12350	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.775
AMV19109.1	AMV16312.1	VT03_14560	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.775
AMV19427.1	AMV16312.1	VT03_16155	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.792
AMV19713.1	AMV16312.1	VT03_17585	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.775
AMV20516.1	AMV16312.1	VT03_21640	VT03_00380	Planctomycete cytochrome C.	Hypothetical protein.	0.775

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.697

expected number of edges:

20

PPI enrichment p-value:

0.0273

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 291

1.77

4.68

1.53e-16

GO:0032543

Mitochondrial translation

4 of 44

2.15

2.72

3.24e-06

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 161

2.02

6.66

1.19e-19

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005761

Mitochondrial ribosome

11 of 63

2.43

10.19

3.69e-24

GO:0005762

Mitochondrial large ribosomal subunit

7 of 36

2.48

6.72

1.42e-14

GO:0044391

Ribosomal subunit

10 of 144

2.03

6.33

4.58e-18

GO:0098798

Mitochondrial protein-containing complex

10 of 173

1.95

5.77

2.25e-17

GO:0005763

Mitochondrial small ribosomal subunit

3 of 24

2.29

2.38

2.53e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8399

Organellar ribosome

11 of 44

2.59

11.36

2.64e-25

CL:8469

Mixed, incl. Ribosomal protein L23, and Ribosomal protein L30p/L7e

5 of 6

3.11

6.4

1.58e-12

CL:8400

Organellar ribosome

6 of 34

2.44

5.58

4.39e-12

CL:8405

Organellar large ribosomal subunit

4 of 15

2.62

3.97

2.95e-08

CL:8409

Mixed, incl. Ribosomal protein L6, and Ribosomal protein L2

2 of 5

2.79

1.76

0.00062

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

8 of 178

1.84

4.14

4.10e-12

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

11 of 274

1.79

4.95

2.18e-17

MAP-392499

Metabolism of proteins

11 of 1159

1.17

1.74

7.07e-11

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005761

Mitochondrial ribosome

11 of 62

2.44

10.22

3.88e-24

GOCC:0005762

Mitochondrial large ribosomal subunit

8 of 35

2.55

8.09

1.86e-17

GOCC:0044391

Ribosomal subunit

11 of 145

2.07

7.21

6.34e-21

GOCC:0098798

Mitochondrial protein complex

11 of 154

2.04

7.01

9.59e-21

GOCC:0005763

Mitochondrial small ribosomal subunit

3 of 27

2.24

2.3

3.39e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 107

1.86

2.61

1.17e-06

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