AMV19697.1 protein (Planctomyces sp. SHPL14)

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

AMV19697.1

Hypothetical protein; GHMP kinases N terminal domain. (319 aa)

Predicted Functional Partners:

AMV16562.1

0.809

fhcA

0.809

AMV18463.1

0.809

fhcC

0.809

mch

0.809

AMV22162.1

0.809

fhcB

0.807

AMV17984.1

0.799

fae_1

0.793

fhcD_1

0.793

Your Current Organism:

Planctomyces sp. SHPL14

NCBI taxonomy Id: 1632864
Other names: P. sp. SH-PL14, Planctomyces sp. SH-PL14

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMV16562.1	AMV17984.1	VT03_01650	VT03_08850	ATP-grasp domain protein.	Hypothetical protein.	0.782
AMV16562.1	AMV18463.1	VT03_01650	VT03_11270	ATP-grasp domain protein.	Hypothetical protein.	0.798
AMV16562.1	AMV19697.1	VT03_01650	VT03_17505	ATP-grasp domain protein.	Hypothetical protein; GHMP kinases N terminal domain.	0.809
AMV16562.1	AMV22162.1	VT03_01650	VT03_29935	ATP-grasp domain protein.	ATP:dephospho-CoA triphosphoribosyl transferase.	0.824
AMV16562.1	fae_1	VT03_01650	VT03_23680	ATP-grasp domain protein.	Formaldehyde-activating enzyme.	0.810
AMV16562.1	fhcA	VT03_01650	VT03_03470	ATP-grasp domain protein.	Formyltransferase/hydrolase complex Fhc subunit A.	0.809
AMV16562.1	fhcB	VT03_01650	VT03_09455	ATP-grasp domain protein.	Formyltransferase/hydrolase complex Fhc subunit B.	0.809
AMV16562.1	fhcC	VT03_01650	VT03_21690	ATP-grasp domain protein.	Formyltransferase/hydrolase complex Fhc subunit C.	0.809
AMV16562.1	fhcD_1	VT03_01650	VT03_25050	ATP-grasp domain protein.	Formyltransferase/hydrolase complex subunit D; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.	0.793
AMV16562.1	mch	VT03_01650	VT03_28970	ATP-grasp domain protein.	Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.	0.809
AMV17984.1	AMV16562.1	VT03_08850	VT03_01650	Hypothetical protein.	ATP-grasp domain protein.	0.782
AMV17984.1	AMV18463.1	VT03_08850	VT03_11270	Hypothetical protein.	Hypothetical protein.	0.809
AMV17984.1	AMV19697.1	VT03_08850	VT03_17505	Hypothetical protein.	Hypothetical protein; GHMP kinases N terminal domain.	0.799
AMV17984.1	AMV22162.1	VT03_08850	VT03_29935	Hypothetical protein.	ATP:dephospho-CoA triphosphoribosyl transferase.	0.778
AMV17984.1	fae_1	VT03_08850	VT03_23680	Hypothetical protein.	Formaldehyde-activating enzyme.	0.775
AMV17984.1	fhcA	VT03_08850	VT03_03470	Hypothetical protein.	Formyltransferase/hydrolase complex Fhc subunit A.	0.790
AMV17984.1	fhcB	VT03_08850	VT03_09455	Hypothetical protein.	Formyltransferase/hydrolase complex Fhc subunit B.	0.792
AMV17984.1	fhcC	VT03_08850	VT03_21690	Hypothetical protein.	Formyltransferase/hydrolase complex Fhc subunit C.	0.786
AMV17984.1	fhcD_1	VT03_08850	VT03_25050	Hypothetical protein.	Formyltransferase/hydrolase complex subunit D; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.	0.782
AMV17984.1	mch	VT03_08850	VT03_28970	Hypothetical protein.	Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.	0.779

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Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.213

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1902600

Proton transmembrane transport

5 of 45

1.91

2.6

1.86e-06

GO:0044237

Cellular metabolic process

11 of 2827

0.45

0.37

0.0017

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015453

Oxidoreduction-driven active transmembrane transporter activity

8 of 48

2.08

5.24

2.61e-13

GO:0009055

Electron transfer activity

10 of 148

1.69

3.92

6.84e-14

GO:0016675

Oxidoreductase activity, acting on a heme group of donors

5 of 25

2.16

3.55

3.77e-08

GO:0016679

Oxidoreductase activity, acting on diphenols and related substances as donors

4 of 9

2.51

3.51

1.88e-07

GO:0004129

Cytochrome-c oxidase activity

4 of 21

2.14

2.73

2.88e-06

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070469

Respirasome

3 of 20

2.04

1.64

0.00059

GO:0005886

Plasma membrane

8 of 1351

0.64

0.47

0.0047

GO:0016021

Integral component of membrane

9 of 1807

0.56

0.42

0.0047

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6359

Oxidoreduction-driven active transmembrane transporter activity, and Cytochrome c

10 of 49

2.17

7.11

2.00e-18

CL:6364

Mixed, incl. Cytochrome-c oxidase activity, and Oxidoreductase activity, acting on diphenols and related substances as donors

8 of 36

2.21

6.0

1.81e-14

CL:6356

Oxidative phosphorylation, and Cytochrome c

11 of 95

1.93

5.86

2.00e-18

CL:6366

Oxidoreduction-driven active transmembrane transporter activity, and Peptidase M16 inactive domain

7 of 25

2.31

5.73

5.18e-13

CL:6397

Respiratory chain, and Insulinase (Peptidase family M16)

3 of 7

2.49

2.36

3.68e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

9 of 101

1.81

4.39

9.07e-14

map01100

Metabolic pathways

11 of 2600

0.49

0.41

0.00029

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070469

Respirasome

6 of 66

1.82

2.94

7.36e-08

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0679

Respiratory chain

2 of 11

2.12

0.95

0.0167

KW-0349

Heme

3 of 80

1.44

0.82

0.0167

KW-0408

Iron

4 of 169

1.24

0.75

0.0155

KW-0479

Metal-binding

5 of 428

0.93

0.59

0.0167

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00116

Cytochrome C oxidase subunit II, periplasmic domain

4 of 4

2.86

3.73

1.30e-07

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