STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XD68_0520Phosphomethylpyrimidine synthase. (424 aa)    
Predicted Functional Partners:
XD68_1433
Phosphomethylpyrimidine kinase.
 
 0.990
XD68_1079
Thiaminephosphate pyrophosphorylase.
  
 
 0.949
thi4
Putative thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
  
  
 0.867
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
 
 0.855
XD68_0625
Putative transcription activator.
  
 
 0.850
XD68_0237
Sulfur carrier protein ThiS.
  
  
 0.838
XD68_0026
UBA/THIF-type NAD/FAD binding protein.
  
  
 0.816
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
     
 0.805
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
    
 0.623
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
 
 0.541
Your Current Organism:
Synergistales bacterium 5424
NCBI taxonomy Id: 1635272
Other names: S. bacterium 54_24, Synergistales bacterium 54_24
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