STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XD68_0739D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (545 aa)    
Predicted Functional Partners:
XD68_0741
2,3-bisphosphoglycerate-independent phosphoglycerate mutase.
    
  0.918
XD68_0738
Phosphoserine aminotransferase apoenzyme.
  
 
 0.896
XD68_0392
Uridine kinase.
   
  0.869
XD68_0740
Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.
  
 
  0.846
XD68_0325
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.782
XD68_1326
Pyruvate-flavodoxin oxidoreductase.
   
 
 0.780
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.674
XD68_0446
Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.629
XD68_0690
FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.
    
 0.610
XD68_0497
Serine acetyltransferase.
     
 0.603
Your Current Organism:
Synergistales bacterium 5424
NCBI taxonomy Id: 1635272
Other names: S. bacterium 54_24, Synergistales bacterium 54_24
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