node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
clpC | clpP_1 | VT85_18075 | VT85_21755 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.879 |
clpC | clpP_2 | VT85_18075 | VT85_21760 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.885 |
clpC | clpS | VT85_18075 | VT85_21930 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.833 |
clpC | dnaK2 | VT85_18075 | VT85_05940 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | Chaperone protein dnaK2; Belongs to the heat shock protein 70 family. | 0.697 |
clpC | dnaK_1 | VT85_18075 | VT85_05970 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK. | 0.697 |
clpC | dnaK_2 | VT85_18075 | VT85_07610 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | 0.697 |
clpC | dnaK_3 | VT85_18075 | VT85_07620 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | 0.707 |
clpC | grpE | VT85_18075 | VT85_12330 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.733 |
clpC | grpE-2 | VT85_18075 | VT85_20950 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.733 |
clpC | mcsB | VT85_18075 | VT85_05110 | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | Putative ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. | 0.740 |
clpP_1 | clpC | VT85_21755 | VT85_18075 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | 0.879 |
clpP_1 | clpP_2 | VT85_21755 | VT85_21760 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.629 |
clpP_1 | clpS | VT85_21755 | VT85_21930 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.476 |
clpP_1 | dnaK2 | VT85_21755 | VT85_05940 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein dnaK2; Belongs to the heat shock protein 70 family. | 0.468 |
clpP_1 | dnaK_1 | VT85_21755 | VT85_05970 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK. | 0.468 |
clpP_1 | dnaK_2 | VT85_21755 | VT85_07610 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | 0.468 |
clpP_1 | dnaK_3 | VT85_21755 | VT85_07620 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Belongs to the heat shock protein 70 family. | 0.468 |
clpP_1 | grpE | VT85_21755 | VT85_12330 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.587 |
clpP_1 | grpE-2 | VT85_21755 | VT85_20950 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.587 |
clpP_2 | clpC | VT85_21760 | VT85_18075 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. | 0.885 |