STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT65143.1Branched-chain alpha-keto acid dehydrogenase subunit E2, pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (464 aa)    
Predicted Functional Partners:
KRT65441.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component, mercuric reductase.
 0.999
KRT65141.1
2-oxo-acid dehydrogenase E1 subunit, homodimeric type, pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
KRT65144.1
Dihydrolipoamide dehydrogenase, dihydrolipoamide dehydrogenase.
 0.999
KRT65050.1
CoA-disulfide reductase.
 
 0.998
KRT65949.1
Cyclic nucleotide-binding protein.
   
 0.983
prs
Ribose-phosphate pyrophosphokinase, ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.979
sucC
succinyl-CoA synthetase subunit beta, succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.974
KRT66132.1
Multi-sensor hybrid histidine kinase.
   
 0.974
KRT62672.1
PAS domain-containing protein.
    
 0.972
KRT64911.1
Two-component sensor histidine kinase.
    
 0.965
Your Current Organism:
Dadabacteria bacterium CSP12
NCBI taxonomy Id: 1640508
Other names: C. Dadabacteria bacterium CSP1-2, Candidatus Dadabacteria bacterium CSP1-2, bacterium CSP1-2
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