STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT63976.1Glutamate racemase, glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (255 aa)    
Predicted Functional Partners:
KRT66065.1
Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
  0.933
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase, UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.850
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.798
murC
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.780
murF
UDP-N-acetylmuramyl-tripeptide synthetase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
    
 0.769
guaB
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.757
KRT65993.1
Cell division protein FtsK/SpoIIIE, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family.
    
 0.686
gdhA
Glutamate dehydrogenase, glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.671
apt
Adenine phosphoribosyltransferase, adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.624
KRT65949.1
Cyclic nucleotide-binding protein.
    
 0.594
Your Current Organism:
Dadabacteria bacterium CSP12
NCBI taxonomy Id: 1640508
Other names: C. Dadabacteria bacterium CSP1-2, Candidatus Dadabacteria bacterium CSP1-2, bacterium CSP1-2
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