STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscAIron-sulfur cluster assembly protein IscA, iron-sulfur cluster assembly protein; Belongs to the HesB/IscA family. (108 aa)    
Predicted Functional Partners:
hscB
Co-chaperone protein HscB, molecular chaperone HscB.
  
 
 0.939
iscU
Iron-sulfur cluster assembly protein IscU, nitrogen fixation protein NifU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
  
 0.929
iscS
Cysteine desulfurase, cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 
 0.872
fdxB
2Fe-2S ferredoxin, ferredoxin, 2Fe-2S.
 
 
 0.837
KRT72839.1
Thioredoxin-like protein.
 
 
 0.836
KRT72208.1
Diguanylate cyclase.
    
 
 0.795
KRT72209.1
Diguanylate cyclase.
    
 
 0.795
nifU
nifU protein.
  
  
 0.690
KRT67893.1
NifU family SUF system FeS assembly protein, nitrogen fixation protein NifU.
  
  
 0.690
hscA
Chaperone protein HscA, molecular chaperone DnaK; Belongs to the heat shock protein 70 family.
  
 
 0.682
Your Current Organism:
Rokubacteria bacterium CSP16
NCBI taxonomy Id: 1640509
Other names: C. Rokubacteria bacterium CSP1-6, Candidatus Rokubacteria bacterium CSP1-6, bacterium CSP1-6
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.