STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT71641.1Acetolactate synthase, acetolactate synthase I/II/III large subunit. (163 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase 3 regulatory subunit, acetolactate synthase I/III small subunit.
  
 0.988
leuD
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
 
 0.900
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 
 0.846
KRT71642.1
Acyl dehydratase.
   
 0.843
KRT71645.1
Hypothetical protein.
   
 0.843
KRT70422.1
Branched-chain amino acid aminotransferase, branched-chain amino acid aminotransferase.
  
 0.822
KRT71646.1
Aspartate aminotransferase, transaminase a, aspat.
    
 0.812
KRT71643.1
Hypothetical protein.
       0.773
KRT71644.1
Hypothetical protein.
       0.773
KRT72259.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.717
Your Current Organism:
Rokubacteria bacterium CSP16
NCBI taxonomy Id: 1640509
Other names: C. Rokubacteria bacterium CSP1-6, Candidatus Rokubacteria bacterium CSP1-6, bacterium CSP1-6
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