STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT71336.1Tetrahydrofolylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (444 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.
 
 0.977
folQ
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.886
accD
acetyl-CoA carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
  
 0.876
KRT75468.1
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase, homocysteine S-methyltransferase.
  
 
 0.812
fhs
Formate--tetrahydrofolate ligase, formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
 
 
 0.789
KRT71335.1
Organic solvent tolerance protein, LPS-assembly protein.
       0.759
KRT70422.1
Branched-chain amino acid aminotransferase, branched-chain amino acid aminotransferase.
    
 0.738
KRT71334.1
DegT/DnrJ/EryC1/StrS family protein; Belongs to the DegT/DnrJ/EryC1 family.
       0.729
trpF
N-(5'-phosphoribosyl)anthranilate isomerase, phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
     
 0.721
trpA
Tryptophan synthase subunit alpha, tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.720
Your Current Organism:
Rokubacteria bacterium CSP16
NCBI taxonomy Id: 1640509
Other names: C. Rokubacteria bacterium CSP1-6, Candidatus Rokubacteria bacterium CSP1-6, bacterium CSP1-6
Server load: low (20%) [HD]