STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ignAsignAl transduction histidine kinase containing a receiver-like protein. (192 aa)    
Predicted Functional Partners:
KRT70617.1
Hypothetical protein.
  
 0.712
KRT70613.1
Adenylyl cyclase.
    
  0.615
KRT75476.1
Adenylate cyclase, adenylate cyclase.
    
  0.602
KRT68365.1
Guanylate cyclase.
    
  0.602
KRT70610.1
Hypothetical protein.
       0.580
KRT70611.1
Cyclic nucleotide-binding: regulatory protein, Crp, CRP/FNR family transcriptional regulator, anaerobic regulatory protein.
       0.580
KRT66662.1
Adenylate/guanylate cyclase.
    
 0.569
KRT66104.1
Histidine kinase.
    
 0.563
mtnP
Putative s-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
 
  
  0.535
KRT72384.1
Two component sigma-54 specific Fis family transcriptional regulator.
  
 
 0.528
Your Current Organism:
Rokubacteria bacterium CSP16
NCBI taxonomy Id: 1640509
Other names: C. Rokubacteria bacterium CSP1-6, Candidatus Rokubacteria bacterium CSP1-6, bacterium CSP1-6
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.