node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT69774.1 | kdsB | XU13_C0061G0011 | XU13_C0061G0010 | Major facilitator superfamily protein. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.774 |
KRT70417.1 | KRT73977.1 | XU13_C0057G0008 | XU13_C0010G0019 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 0.416 |
KRT70417.1 | kdsA | XU13_C0057G0008 | XU13_C0010G0021 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 2-dehydro-3-deoxyphosphooctonate aldolase, 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.743 |
KRT70417.1 | kdsB | XU13_C0057G0008 | XU13_C0061G0010 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.820 |
KRT70417.1 | kdtA | XU13_C0057G0008 | XU13_C0057G0003 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.905 |
KRT70417.1 | kpsF | XU13_C0057G0008 | XU13_C0010G0020 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.790 |
KRT70417.1 | lpxB | XU13_C0057G0008 | XU13_C0057G0005 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.992 |
KRT70417.1 | lpxC | XU13_C0057G0008 | XU13_C0002G0029 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.926 |
KRT70417.1 | lpxD | XU13_C0057G0008 | XU13_C0057G0009 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.997 |
KRT70417.1 | lpxK | XU13_C0057G0008 | XU13_C0057G0002 | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase, tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.899 |
KRT73977.1 | KRT70417.1 | XU13_C0010G0019 | XU13_C0057G0008 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.416 |
KRT73977.1 | kdsA | XU13_C0010G0019 | XU13_C0010G0021 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 2-dehydro-3-deoxyphosphooctonate aldolase, 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.990 |
KRT73977.1 | kdsB | XU13_C0010G0019 | XU13_C0061G0010 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.990 |
KRT73977.1 | kdtA | XU13_C0010G0019 | XU13_C0057G0003 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.809 |
KRT73977.1 | kpsF | XU13_C0010G0019 | XU13_C0010G0020 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.995 |
KRT73977.1 | lpxB | XU13_C0010G0019 | XU13_C0057G0005 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.431 |
KRT73977.1 | lpxC | XU13_C0010G0019 | XU13_C0002G0029 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.449 |
KRT73977.1 | lpxD | XU13_C0010G0019 | XU13_C0057G0009 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.439 |
KRT73977.1 | lpxK | XU13_C0010G0019 | XU13_C0057G0002 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | Tetraacyldisaccharide 4'-kinase, tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.463 |
kdsA | KRT70417.1 | XU13_C0010G0021 | XU13_C0057G0008 | 2-dehydro-3-deoxyphosphooctonate aldolase, 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.743 |