KRT64020.1 protein (Chloroflexi bacterium CSP14)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

KRT64020.1

Formyl-CoA transferase, formyl-CoA transferase; Belongs to the CoA-transferase III family. (405 aa)

Predicted Functional Partners:

KRT64022.1

0.854

KRT64021.1

0.838

KRT63405.1

0.632

KRT63503.1

0.616

KRT63565.1

0.570

KRT62811.1

0.570

KRT63502.1

0.560

KRT62312.1

0.559

KRT63826.1

0.551

KRT63603.1

0.548

Your Current Organism:

Chloroflexi bacterium CSP14

NCBI taxonomy Id: 1640513
Other names: C. bacterium CSP1-4, Chloroflexi bacterium CSP1-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRT62312.1	KRT63405.1	XU10_C0032G0028	XU10_C0011G0017	Putative oxidoreductase.	Hypothetical protein.	0.693
KRT62312.1	KRT63826.1	XU10_C0032G0028	XU10_C0007G0086	Putative oxidoreductase.	FMN adenylyltransferase, riboflavin kinase, riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family.	0.744
KRT62312.1	KRT64020.1	XU10_C0032G0028	XU10_C0005G0044	Putative oxidoreductase.	Formyl-CoA transferase, formyl-CoA transferase; Belongs to the CoA-transferase III family.	0.559
KRT62811.1	KRT63405.1	XU10_C0020G0030	XU10_C0011G0017	Acetolactate synthase large subunit, acetolactate synthase I/II/III large subunit.	Hypothetical protein.	0.445
KRT62811.1	KRT63603.1	XU10_C0020G0030	XU10_C0009G0050	Acetolactate synthase large subunit, acetolactate synthase I/II/III large subunit.	Succinate dehydrogenase subunit B, succinate dehydrogenase iron-sulfur subunit.	0.477
KRT62811.1	KRT64020.1	XU10_C0020G0030	XU10_C0005G0044	Acetolactate synthase large subunit, acetolactate synthase I/II/III large subunit.	Formyl-CoA transferase, formyl-CoA transferase; Belongs to the CoA-transferase III family.	0.570
KRT63405.1	KRT62312.1	XU10_C0011G0017	XU10_C0032G0028	Hypothetical protein.	Putative oxidoreductase.	0.693
KRT63405.1	KRT62811.1	XU10_C0011G0017	XU10_C0020G0030	Hypothetical protein.	Acetolactate synthase large subunit, acetolactate synthase I/II/III large subunit.	0.445
KRT63405.1	KRT63503.1	XU10_C0011G0017	XU10_C0010G0036	Hypothetical protein.	Hypothetical protein.	0.614
KRT63405.1	KRT63565.1	XU10_C0011G0017	XU10_C0009G0012	Hypothetical protein.	Thiamine pyrophosphate protein, acetolactate synthase I/II/III large subunit; Belongs to the TPP enzyme family.	0.445
KRT63405.1	KRT64020.1	XU10_C0011G0017	XU10_C0005G0044	Hypothetical protein.	Formyl-CoA transferase, formyl-CoA transferase; Belongs to the CoA-transferase III family.	0.632
KRT63405.1	KRT64021.1	XU10_C0011G0017	XU10_C0005G0045	Hypothetical protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.599
KRT63502.1	KRT63503.1	XU10_C0010G0035	XU10_C0010G0036	LAO/AO transporter ATPase, LAO/AO transport system kinase.	Hypothetical protein.	0.998
KRT63502.1	KRT64020.1	XU10_C0010G0035	XU10_C0005G0044	LAO/AO transporter ATPase, LAO/AO transport system kinase.	Formyl-CoA transferase, formyl-CoA transferase; Belongs to the CoA-transferase III family.	0.560
KRT63502.1	KRT64022.1	XU10_C0010G0035	XU10_C0005G0046	LAO/AO transporter ATPase, LAO/AO transport system kinase.	methylmalonyl-CoA mutase large subunit.	0.987
KRT63503.1	KRT63405.1	XU10_C0010G0036	XU10_C0011G0017	Hypothetical protein.	Hypothetical protein.	0.614
KRT63503.1	KRT63502.1	XU10_C0010G0036	XU10_C0010G0035	Hypothetical protein.	LAO/AO transporter ATPase, LAO/AO transport system kinase.	0.998
KRT63503.1	KRT63603.1	XU10_C0010G0036	XU10_C0009G0050	Hypothetical protein.	Succinate dehydrogenase subunit B, succinate dehydrogenase iron-sulfur subunit.	0.581
KRT63503.1	KRT64020.1	XU10_C0010G0036	XU10_C0005G0044	Hypothetical protein.	Formyl-CoA transferase, formyl-CoA transferase; Belongs to the CoA-transferase III family.	0.616
KRT63503.1	KRT64022.1	XU10_C0010G0036	XU10_C0005G0046	Hypothetical protein.	methylmalonyl-CoA mutase large subunit.	0.998

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Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.922

expected number of edges:

10

PPI enrichment p-value:

1.04e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006644

Phospholipid metabolic process

6 of 125

1.74

2.42

1.48e-06

GO:0008654

Phospholipid biosynthetic process

5 of 95

1.78

2.21

8.94e-06

GO:0006650

Glycerophospholipid metabolic process

5 of 97

1.77

2.2

8.94e-06

GO:0006629

Lipid metabolic process

7 of 291

1.44

1.91

1.74e-06

GO:0046474

Glycerophospholipid biosynthetic process

4 of 76

1.78

1.79

0.00013

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016780

Phosphotransferase activity, for other substituted phosphate groups

2 of 11

2.32

0.9

0.0223

GO:0042578

Phosphoric ester hydrolase activity

4 of 174

1.42

0.89

0.0103

GO:0003824

Catalytic activity

10 of 3163

0.56

0.4

0.0103

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15229

Inositol phosphate metabolism

3 of 12

2.46

1.84

0.00038

CL:9328

Mixed, incl. Glycerophospholipid catabolic process, and Cell cycle G1/S phase transition

3 of 13

2.42

1.83

0.00038

CL:13210

Phospholipid metabolism, and Phosphatidylserine decarboxylase

2 of 6

2.58

1.31

0.0041

CL:9330

Mixed, incl. Cell cycle G1/S phase transition, and SPX domain

2 of 7

2.52

1.27

0.0047

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00564

Glycerophospholipid metabolism

5 of 76

1.88

2.74

5.88e-07

map00562

Inositol phosphate metabolism

3 of 43

1.9

1.62

0.00050

map00030

Pentose phosphate pathway

2 of 21

2.04

1.16

0.0060

map04070

Phosphatidylinositol signaling system

2 of 48

1.68

0.82

0.0228

map01100

Metabolic pathways

8 of 1691

0.74

0.61

0.00054

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1855183

Synthesis of IP2, IP, and Ins in the cytosol

2 of 5

2.66

1.12

0.0093

MAP-71336

Pentose phosphate pathway

2 of 14

2.22

0.87

0.0242

MAP-1483249

Inositol phosphate metabolism

2 of 16

2.16

0.87

0.0242

MAP-71387

Metabolism of carbohydrates

3 of 137

1.4

0.68

0.0362

MAP-1430728

Metabolism

7 of 1121

0.86

0.59

0.0093

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0460

Magnesium

3 of 46

1.88

1.36

0.0019

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00459

Inositol monophosphatase family

2 of 2

3.06

1.34

0.0038

PF01066

CDP-alcohol phosphatidyltransferase

2 of 5

2.66

1.2

0.0066

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR020583

Inositol monophosphatase, metal-binding site

2 of 2

3.06

1.08

0.0112

IPR020550

Inositol monophosphatase, conserved site

2 of 2

3.06

1.08

0.0112

IPR000760

Inositol monophosphatase-like

2 of 2

3.06

1.08

0.0112

IPR043130

CDP-alcohol phosphatidyltransferase, transmembrane domain

2 of 5

2.66

1.07

0.0112

IPR000462

CDP-alcohol phosphatidyltransferase

2 of 5

2.66

1.07

0.0112

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