STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase (GSA), Glutamate-1-semialdehyde aminotransferase, GSA-AT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family.
 
 
 0.960
hemA
glutamyl-tRNA reductase (GluTR); Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.917
hemC
Porphobilinogen deaminase, hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.877
KRT69968.1
uroporphyrin-III C-methyltransferase, uroporphyrinogen III methyltransferase / synthase.
 
 
 0.858
fabD
Malonyl CoA-acyl carrier protein transacylase, [acyl-carrier-protein] S-malonyltransferase.
    
 0.804
KRT69967.1
uroporphyrin-III C-methyltransferase, uroporphyrinogen III methyltransferase / synthase; Belongs to the precorrin methyltransferase family.
  
 
 0.795
KRT69066.1
uroporphyrin-III C-methyltransferase, uroporphyrinogen III methyltransferase / synthase; Belongs to the precorrin methyltransferase family.
  
 
 0.795
lysC
Aspartokinase; Belongs to the aspartokinase family.
   
 
 0.789
mtdB
Methylene tetrahydromethanopterin dehydrogenase (mtdB).
  
 0.766
argJ
Arginine biosynthesis bifunctional protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
 0.697
Your Current Organism:
candidate division NC10 bacterium CSP15
NCBI taxonomy Id: 1640516
Other names: c. division NC10 bacterium CSP1-5, candidate division NC10 bacterium CSP1-5
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