STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT70043.1Kbl, 2-amino-3-ketobutyrate coenzyme A ligase, AKB ligase, Glycine C-acetyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.943
fabD
Malonyl CoA-acyl carrier protein transacylase, [acyl-carrier-protein] S-malonyltransferase.
 
 
 0.922
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
 
 0.907
bioB
Biotin synthase, biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
 0.901
KRT70568.1
Glucose dehydrogenase.
  
 
 0.789
KRT70186.1
Threonine dehydrogenase and related Zn-dependent dehydrogenases.
 
 
 0.789
KRT70463.1
Multi-sensor hybrid histidine kinase.
  
 
 0.783
KRT70743.1
biotin--acetyl-CoA-carboxylase ligase, BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
  
 
 0.766
hemB
Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family.
    
 0.716
KRT68168.1
Response regulator receiver protein.
  
 
 0.715
Your Current Organism:
candidate division NC10 bacterium CSP15
NCBI taxonomy Id: 1640516
Other names: c. division NC10 bacterium CSP1-5, candidate division NC10 bacterium CSP1-5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.