STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.999
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
 0.999
SAMN05216323_101441
Lipoate--protein ligase.
 
 
 0.989
SAMN05216323_101912
Dihydrolipoyl dehydrogenase.
 
  
 0.946
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
 0.910
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
   
 0.905
SAMN05216323_100434
2-oxoglutarate dehydrogenase E1 component.
   
 
 0.890
SAMN05216323_101130
2-oxoisovalerate dehydrogenase E1 component.
   
 
 0.889
SAMN05216323_101537
Long-chain acyl-CoA synthetase.
  
 0.889
SAMN05216323_102442
Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.
   
 
 0.889
Your Current Organism:
Williamwhitmania taraxaci
NCBI taxonomy Id: 1640674
Other names: Bacteroidales bacterium A7P-90m, DSM 100563, JCM 30888, W. taraxaci, Williamwhitmania taraxaci Pikuta et al. 2017, bacterium A7P-90m, strain A7P-90m
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