STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XD89_0803Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (248 aa)    
Predicted Functional Partners:
XD89_0145
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.992
XD89_0502
Aminomethyltransferase; Belongs to the GcvT family.
  
 
 0.940
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.909
XD89_0335
Pyruvate-flavodoxin oxidoreductase.
    
 0.895
XD89_0965
Pyruvate-flavodoxin oxidoreductase.
    
 0.895
folD
folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.838
XD89_0368
Sugar-phosphate isomerase, RpiB/LacA/LacB family.
    
  0.781
XD89_0203
Glutamate synthase.
  
 
 0.726
gcvPB
Putative glycine dehydrogenase [decarboxylating] subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
    
 0.720
XD89_0811
MerR family transcriptional regulator.
  
 
 0.719
Your Current Organism:
Anaerolineae bacterium 4920
NCBI taxonomy Id: 1641376
Other names: A. bacterium 49_20, Anaerolineae bacterium 49_20
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