STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLR61725.1Nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (293 aa)    
Predicted Functional Partners:
KLR61726.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.999
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 
 0.999
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.964
KLR60262.1
PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; amidohydrolase, PncC family; molybdenum cofactor synthesis domain.
    
 0.912
KLR61324.1
Putative ATPase/kinase involved in NAD metabolism; PFAM: AAA domain; Citrate lyase ligase C-terminal domain; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type.
     
 0.896
KLR59864.1
PFAM: Dehydrogenase E1 component; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
    
 0.835
KLR61347.1
Hypothetical protein; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; MazG nucleotide pyrophosphohydrolase domain.
    
  0.826
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
   
 0.790
KLR60518.1
PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED.
    
 0.778
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.707
Your Current Organism:
Actinobacteria bacterium IMCC26207
NCBI taxonomy Id: 1641811
Other names: A. bacterium IMCC26207
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