STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCM55193.1Adenine deaminase {ECO:0000255|HAMAP-Rule:MF_01962}; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (339 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase {ECO:0000255|HAMAP-Rule:MF_00004}; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.954
punA
Purine nucleoside phosphorylase 1 {ECO:0000303|}; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.929
hpt
Hypoxanthine-guanine phosphoribosyltransferase; sp|P0A5T1|HPRT_MYCBO,sp|P9WHQ8|HPRT_MYCTO, sp|P9WHQ9|HPRT_MYCTU;evalue=9e-029; PctID=40.12; score=126; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.920
SCM58220.1
AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465.
    
 0.905
SCM55192.1
Putative glycosidase Rv0584; sp|O86365|Y584_MYCTU;evalue=7e-036; PctID=40.36; score=152.
       0.525
guaA
GMP synthase [glutamine-hydrolyzing] {ECO:0000255|HAMAP-Rule:MF_00344}; Catalyzes the synthesis of GMP from XMP.
  
  
 0.509
Nt5c1a3
Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143.
     
  0.499
guaB
Inosine-5'-monophosphate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01964}; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.480
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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