STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cshADEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'-and 3'-directions, has RNA-dependent ATPase activity. subfamily; sp|Q5L3G9|CSHA_GEOKA;evalue=9e-097; PctID=47.89; score=354; Belongs to the DEAD box helicase family. (575 aa)    
Predicted Functional Partners:
recQ3
ATP-dependent DNA helicase RecQ; Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase. ProRule:PRU00328}. Sequence=AAA24517.1; Type=Erroneous initiation; Evidence=; Sequence=AAA67618.1; Type=Erroneous initiation; Evidence=; sp|P15043|RECQ_ECOLI;evalue=2e-076; PctID=44.48; score=287.
 
0.940
recQ1
DNA helicase. ProRule:PRU00328}; sp|P71359|RECQ_HAEIN;evalue=4e-106; PctID=36.69; score=386.
 
0.938
pnp
Polyribonucleotide nucleotidyltransferase {ECO:0000255|HAMAP-Rule:MF_01595}; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
 
 0.850
nnrD
ADP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_01965}; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific [...]
  
 0.834
SCM56563.1
Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
 0.808
rplC
50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325}; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.806
fusA
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. domain; sp|B4U741|EFG_HYDS0;evalue=2e-034; PctID=44.13; score=147.
  
 0.789
fusA-2
Elongation factor G {ECO:0000255|HAMAP-Rule:MF_00054}; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPa [...]
   
 0.783
SCM55114.1
Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.770
rplD
50S ribosomal protein L4 {ECO:0000255|HAMAP-Rule:MF_01328}; Forms part of the polypeptide exit tunnel.
  
 0.769
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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