STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
yteRUnsaturated rhamnogalacturonyl hydrolase YteR; Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D-glucuronic acid at the non-reducing terminus, although the active pockets of YesR and UGL are very similar. enopyranuronosyl)-alpha-L-rhamnopyranose + H(2)O = 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose. Kinetic parameters: KM=100 uM for unsaturated rhamnogalacturonan disaccharide (at pH 4 and 30 degrees Celsius); p [...] (395 aa)    
Predicted Functional Partners:
pgl1
Polygalacturonase; Seems to regulate the surface properties of the bacterium in the presence of plant cells or plant cell extracts. galactosiduronic linkages in pectate and other galacturonans. extract; sp|P27644|PGLR_RHIRD;evalue=2e-027; PctID=36.40; score=124; Belongs to the glycosyl hydrolase 28 family.
  
 0.989
SCM55163.1
Putative polygalacturonase At3g15720; sp|Q9LW07|PGLR3_ARATH;evalue=6e-007; PctID=32.93; score=55.8; Belongs to the glycosyl hydrolase 28 family.
     0.977
rhgT
Rhamnogalacturonan acetylesterase RhgT; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity, and shows strong preference for glucose pentaacetate, beta-naphthylacetate, and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan. diethylpyrocarbonate at 5 mM and completely inhibited by phenylmethylsulfonyl fluoride (PMSF) at 50 mM. Dimethyl phosphite achieves only a 53% inhibition. Also inhibited by metal ions (magnesium, manganese and calcium) and chelating agent (EDTA) at the same level [...]
 
    0.952
SCM55358.1
Pectinesterase 31; Acts in the modification of cell walls via demethylesterification of cell wall pectin (By similarity). Acts in a blockwise manner, resulting in a cell wall rigidification. inhibited by kiwi pectin methylesterase inhibitor (PMEI). pH dependence: Optimum pH is 8.0-8.5; Temperature dependence: Fully active at 0 or 30 degrees Celsius, inactive at 55 degrees Celsius.; D-gluconate from pectin: step 1/5. siliques. family that do not contain a transmembrane or a signal peptide; sp|Q9LVQ0|PME31_ARATH;evalue=6e-039; PctID=45.00; score=163.
  
 0.948
SCM55360.1
Pectinesterase 31; Acts in the modification of cell walls via demethylesterification of cell wall pectin (By similarity). Acts in a blockwise manner, resulting in a cell wall rigidification. inhibited by kiwi pectin methylesterase inhibitor (PMEI). pH dependence: Optimum pH is 8.0-8.5; Temperature dependence: Fully active at 0 or 30 degrees Celsius, inactive at 55 degrees Celsius.; D-gluconate from pectin: step 1/5. siliques. family that do not contain a transmembrane or a signal peptide; sp|Q9LVQ0|PME31_ARATH;evalue=1e-063; PctID=47.69; score=244.
  
 0.937
plyC
Putative pectate lyase C; Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity). galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends. Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence=; Note=Binds 1 Ca(2+) ion per [...]
 
  
 0.928
SCM56495.1
Putative protein {ECO:0000313|EMBL:EKN20892,1}; tr|K5Z2C0|K5Z2C0_9PORP;evalue=0.0; PctID=55.26; score=778.
 
     0.888
SIAE
Sialate O-acetylesterase; Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. acetylneuraminate + acetate. Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9HAT2-1; Name=2; IsoId=Q9HAT2-2; Sequence=VSP_018993; Note=No experimental confirmation available; testis, prostate, and colon. manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and [...]
 
    0.878
SCM56503.1
Putative protein {ECO:0000313|EMBL:EHB93456,1}; tr|G5H5L7|G5H5L7_9BACT;evalue=0.0; PctID=67.42; score=696; Belongs to the glycosyl hydrolase 28 family.
     0.783
kduI
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase {ECO:0000255|HAMAP-Rule:MF_00687}; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.778
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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