STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribCRiboflavin biosynthesis protein RibC; sp|P54575|RIBC_BACSU;evalue=3e-042; PctID=35.02; score=172; Belongs to the ribF family. (298 aa)    
Predicted Functional Partners:
truB
tRNA pseudouridine synthase B {ECO:0000255|HAMAP-Rule:MF_01080}; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.941
ribE
Riboflavin synthase; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2; sp|P50854|RISA_ACTPL;evalue=1e-035; PctID=39.90; score=149.
  
 
 0.928
rfbC
Involved in O-antigen biosynthesis; sp|Q50864|RFBC_MYXXA;evalue=3e-012; PctID=26.42; score=73.2.
 
    0.870
cmk
Cytidylate kinase {ECO:0000255|HAMAP-Rule:MF_00238}; sp|A6LIB2|KCY_PARD8;evalue=2e-072; PctID=61.78; score=272.
  
 0.821
yvgN
Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis. NADPH; sp|O32210|GR_BACSU;evalue=5e-069; PctID=47.21; score=261.
  
    0.777
ribH
6,7-dimethyl-8-ribityllumazine synthase {ECO:0000255|HAMAP-Rule:MF_00178}; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.776
coaD
Phosphopantetheine adenylyltransferase {ECO:0000255|HAMAP-Rule:MF_00151}; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
   
 0.754
mnmA
tRNA-specific 2-thiouridylase MnmA {ECO:0000255|HAMAP-Rule:MF_00144}; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. Rule:MF_00144}; sp|A6LIF1|MNMA_PARD8;evalue=5e-159; PctID=73.16; score=560.
 
    0.714
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.669
coaE
Dephospho-CoA kinase {ECO:0000255|HAMAP-Rule:MF_00376}; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.612
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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