STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purFAmidophosphoribosyltransferase{ECO:0000255|HAMA P-Rule:MF_01931}; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H(2)O. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Note=Binds 1 Mg(2+) ion per subunit; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. purine/pyrimidine phosphoribosyltransferase family; sp|Q9L6B8|PUR1_PASMU;evalue=1e-008; PctID=37.17; score=62.0. (642 aa)    
Predicted Functional Partners:
purD
Phosphoribosylamine-glycine ligase {ECO:0000255|HAMAP-Rule:MF_00138}; sp|Q8KBV8|PUR2_CHLTE;evalue=3e-097; PctID=45.43; score=355; Belongs to the GARS family.
 0.998
purL
Putative phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
 
 0.991
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase {ECO:0000255|HAMAP-Rule:MF_00137}; sp|Q7MVR8|PUR7_PORGI;evalue=2e-129; PctID=70.51; score=462; Belongs to the SAICAR synthetase family.
 
 
 0.986
purM
Phosphoribosylformylglycinamidine cyclo-ligase; sp|Q57656|PUR5_METJA;evalue=3e-012; PctID=34.07; score=73.2.
 
  
 0.975
pyr1-3
This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). ADP + phosphate + L-glutamate + carbamoyl phosphate. + N-carbamoyl-L-aspartate. aspartate. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 1 zinc ion per subunit (for dihydroorotase activity); phosphorylation. 5-phosphoribose 1-diphosphate is an activator while UMP is an inhibitor of the CPSase reaction. pathway; (S)-dihydroorotate from bicarbonate: step 1/3. pathway; (S)-dihydroorotate from bicarbonate: step 2/3. pathway; (S)-dihydroorotate fr [...]
  
 
 0.959
purH
Bifunctional purine biosynthesis protein PurH {ECO:0000255|HAMAP-Rule:MF_00139}; sp|Q8A155|PUR9_BACTN;evalue=0.0; PctID=66.60; score=664.
 
 
 0.953
purB
Adenylosuccinate lyase; sp|Q54J34|PUR8_DICDI;evalue=2e-142; PctID=58.77; score=506; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 
 0.951
gltB
Ferredoxin-dependent glutamate synthase 1; sp|P55037|GLTB_SYNY3;evalue=0.0; PctID=51.63; score=1462.
    
 0.950
PUR3
Phosphoribosylglycinamide formyltransferase, chloroplastic; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.945
CAD
This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). ADP + phosphate + L-glutamate + carbamoyl phosphate. + N-carbamoyl-L-aspartate. aspartate. Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence=; Note=Binds 3 Zn(2+) ions per subunit (for dihydroorotase activity); phosphorylation. 5-phosphoribose 1-diphosphate is an activator while UMP is an inhibitor of the CPSase reaction (By similarity). pathway; (S)-dihydroorotate from bicarbonate: step 1/3. pathway; (S)-dihydroorotate from bicarbonate: step 2/3. pathway; (S [...]
  
  
 0.941
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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