node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nt5c1a3 | SCM55193.1 | ING2E5A_0575 | ING2E5A_0108 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | Adenine deaminase {ECO:0000255|HAMAP-Rule:MF_01962}; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.499 |
Nt5c1a3 | SCM58220.1 | ING2E5A_0575 | ING2E5A_1713 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | 0.900 |
Nt5c1a3 | SCM58340.1 | ING2E5A_0575 | ING2E5A_1766 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | Snake venom 5'-nucleotidase; Hydrolyzes nucleotides into nucleosides (By similarity). Snake venom 5'-nucleotidases are widely distributed among venomous snake taxa, but there is a lack of information about their biological activities. They have been shown to inhibit platelet aggregation. This effect may be due to the liberation of inhibitory AMP or adenosine by its action on ADP released upon initiation of aggregation. Venom 5'-nucleotidases are also known to synergistically act in vivo with other toxins like ADPases, phospholipases, and disintegrins to exert a more pronounced anti-coa [...] | 0.900 |
Nt5c1a3 | adk | ING2E5A_0575 | ING2E5A_0480 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | Adenylate kinase {ECO:0000255|HAMAP-Rule:MF_00235}; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.900 |
Nt5c1a3 | apt | ING2E5A_0575 | ING2E5A_0252 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | Adenine phosphoribosyltransferase {ECO:0000255|HAMAP-Rule:MF_00004}; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
Nt5c1a3 | cdd | ING2E5A_0575 | ING2E5A_1317 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.900 |
Nt5c1a3 | punA | ING2E5A_0575 | ING2E5A_1026 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | Purine nucleoside phosphorylase 1 {ECO:0000303|}; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.900 |
Nt5c1a3 | purB | ING2E5A_0575 | ING2E5A_1897 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | Adenylosuccinate lyase; sp|Q54J34|PUR8_DICDI;evalue=2e-142; PctID=58.77; score=506; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.900 |
Nt5c1a3 | surE | ING2E5A_0575 | ING2E5A_0693 | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | 5'-nucleotidase SurE {ECO:0000255|HAMAP-Rule:MF_00060}; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
SCM55193.1 | Nt5c1a3 | ING2E5A_0108 | ING2E5A_0575 | Adenine deaminase {ECO:0000255|HAMAP-Rule:MF_01962}; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | 0.499 |
SCM55193.1 | SCM58220.1 | ING2E5A_0108 | ING2E5A_1713 | Adenine deaminase {ECO:0000255|HAMAP-Rule:MF_01962}; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | 0.905 |
SCM55193.1 | apt | ING2E5A_0108 | ING2E5A_0252 | Adenine deaminase {ECO:0000255|HAMAP-Rule:MF_01962}; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenine phosphoribosyltransferase {ECO:0000255|HAMAP-Rule:MF_00004}; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.954 |
SCM55193.1 | punA | ING2E5A_0108 | ING2E5A_1026 | Adenine deaminase {ECO:0000255|HAMAP-Rule:MF_01962}; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Purine nucleoside phosphorylase 1 {ECO:0000303|}; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.929 |
SCM58218.1 | SCM58220.1 | ING2E5A_1712 | ING2E5A_1713 | DNA polymerase III, delta subunit {ECO:0000313|EMBL:EGK02935,1}; tr|F5IUN5|F5IUN5_9PORP;evalue=3e-107; PctID=55.52; score=395. | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | 0.663 |
SCM58220.1 | Nt5c1a3 | ING2E5A_1713 | ING2E5A_0575 | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | Cytosolic 5'-nucleotidase 1A; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia (By similarity). + phosphate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; sp|A3KFX0|5NT1A_MOUSE;evalue=9e-034; PctID=35.55; score=143. | 0.900 |
SCM58220.1 | SCM55193.1 | ING2E5A_1713 | ING2E5A_0108 | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | Adenine deaminase {ECO:0000255|HAMAP-Rule:MF_01962}; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.905 |
SCM58220.1 | SCM58218.1 | ING2E5A_1713 | ING2E5A_1712 | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | DNA polymerase III, delta subunit {ECO:0000313|EMBL:EGK02935,1}; tr|F5IUN5|F5IUN5_9PORP;evalue=3e-107; PctID=55.52; score=395. | 0.663 |
SCM58220.1 | SCM58340.1 | ING2E5A_1713 | ING2E5A_1766 | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | Snake venom 5'-nucleotidase; Hydrolyzes nucleotides into nucleosides (By similarity). Snake venom 5'-nucleotidases are widely distributed among venomous snake taxa, but there is a lack of information about their biological activities. They have been shown to inhibit platelet aggregation. This effect may be due to the liberation of inhibitory AMP or adenosine by its action on ADP released upon initiation of aggregation. Venom 5'-nucleotidases are also known to synergistically act in vivo with other toxins like ADPases, phospholipases, and disintegrins to exert a more pronounced anti-coa [...] | 0.903 |
SCM58220.1 | adk | ING2E5A_1713 | ING2E5A_0480 | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | Adenylate kinase {ECO:0000255|HAMAP-Rule:MF_00235}; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.900 |
SCM58220.1 | apt | ING2E5A_1713 | ING2E5A_0252 | AMP nucleosidase {ECO:0000313|EMBL:CEA15793,1}; tr|A0A098C048|A0A098C048_9PORP;evalue=1e-128; PctID=85.66; score=465. | Adenine phosphoribosyltransferase {ECO:0000255|HAMAP-Rule:MF_00004}; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.909 |