STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase {ECO:0000255|HAMAP-Rule:MF_00113}; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (411 aa)    
Predicted Functional Partners:
tgt
Queuine tRNA-ribosyltransferase {ECO:0000255|HAMAP-Rule:MF_00168}; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack [...]
 
 0.970
queG
Epoxyqueuosine reductase {ECO:0000255|HAMAP-Rule:MF_00916}; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). epoxyqueuosine(34) in tRNA + reduced acceptor. Rule:MF_00916}; sp|E6X4P3|QUEG_CELAD;evalue=2e-082; PctID=49.83; score=306.
 
  
 0.753
ruvB
Holliday junction ATP-dependent DNA helicase RuvB {ECO:0000255|HAMAP-Rule:MF_00016}; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
  
 0.680
SCM58486.1
Putative protein {ECO:0000313|EMBL:CEA16096,1}; tr|A0A098C0Z0|A0A098C0Z0_9PORP;evalue=4e-109; PctID=64.86; score=401.
       0.581
ruvA
Holliday junction ATP-dependent DNA helicase RuvA {ECO:0000255|HAMAP-Rule:MF_00031}; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
  
 0.560
SCM58488.1
Putative secreted protein {ECO:0000313|EMBL:CEA16097,1}; tr|A0A098C2E1|A0A098C2E1_9PORP;evalue=8e-064; PctID=65.19; score=249.
       0.485
pycB3
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. oxaloacetate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Name=Co(2+); Xref=ChEBI:CHEBI:48828; exceeded the ATP one, and by high concentration of ATP and alpha-ketoglutarate. pH dependence: Optimum pH is 8.5; Temperature dependence: Optimum temperature is 80-90 degrees Celsius.; Evidence=; sp|Q58628|PYCB_METJA;evalue=1e-028; PctID=32.58; score=128.
  
  
 0.474
rnc
Ribonuclease 3 {ECO:0000255|HAMAP-Rule:MF_00104}; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.442
oadB
Oxaloacetate decarboxylase beta chain; Lyase and sodium transporter. Name=Na(+); Xref=ChEBI:CHEBI:29101; Evidence=; membrane protein; sp|Q9RF98|OADB_HAEDU;evalue=5e-067; PctID=43.25; score=255.
       0.434
4.1.1.3
Hypothetical protein; Evalue=; PctID=; score=.
       0.434
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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