STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppPUndecaprenyl-diphosphatase {ECO:0000255|HAMAP-Rule:MF_01006}; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (294 aa)    
Predicted Functional Partners:
lpxF
Removes the 4'-phosphate group from lipid A species. Absence of phosphate groups in lipid A renders the bacteria resistant to host-derived cationic antimicrobial peptides (CAMP) and allows it to camouflage itself from the host innate immune response. Removal of the 4'-phosphate may be required to generate the substrate for deacylation of the pentaacyl lipid A to the tetraccylated lipid A species. biosynthesis; Multi-pass membrane protein decreased removal of 4'-phosphate from lipid A species. Accumulates pentaacylated 4'-phosphate lipid A with concomitant loss of the usual non-phosphor [...]
  
 
 0.923
uppS
Isoprenyl transferase {ECO:0000255|HAMAP-Rule:MF_01139}; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
     
 0.919
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase{ECO:0000255|HAMAP-Rule:MF_00038}; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
    
 0.915
truB
tRNA pseudouridine synthase B {ECO:0000255|HAMAP-Rule:MF_01080}; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.805
SCM58599.1
Putative protein {ECO:0000313|EMBL:CDD33533,1}; tr|R6YC86|R6YC86_9BACE;evalue=7e-015; PctID=57.97; score=85.5.
       0.779
queA-2
S-adenosylmethionine:tRNA ribosyltransferase-isomerase {ECO:0000255|HAMAP-Rule:MF_00113}; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
   
 0.765
ftsX
Required for cell division and gliding motility; Multi-pass membrane protein septa. Filaments cross walls but cells fail to separate. Gliding motility defects. Resistant to infection by a number of F.johnsoniae bacteriophages. FtsX subfamily; sp|A5FMG4|FTSX_FLAJ1;evalue=4e-020; PctID=28.65; score=99.0; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
  
    0.686
fol1
Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis. dihydropterin + glycolaldehyde. + 6-hydroxymethyl-7,8-dihydropterin diphosphate. + 4-aminobenzoate = diphosphate + dihydropteroate. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Kinetic parameters: KM=2.3 uM for 7,8-dihydroneopterin; KM=3.6 uM for 6-hydroxymethyl-7,8-dihydropterin; Vmax=36 nmol/min/mg enzyme for 7,8-dihydroneopterin; pH dependence: Optimum pH is 8; amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4. amino [...]
       0.635
glgE
Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase {ECO:0000255|HAMAP-Rule:MF_02124}; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. glucosyl)(n) = phosphate + ((1->4)-alpha-D-glucosyl)(n+2). subfamily; sp|Q3J3M8|GLGE_RHOS4,sp|Q9JN46|GLGE_RHOSH;evalue=2e-009; PctID=32.97; score=64.3.
 
     0.564
ylbK1
Putative NTE family protein YlbK; sp|O34731|YLBK_BACSU;evalue=5e-019; PctID=26.47; score=95.1.
       0.470
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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