STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribERiboflavin synthase; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2; sp|P50854|RISA_ACTPL;evalue=1e-035; PctID=39.90; score=149. (201 aa)    
Predicted Functional Partners:
ribBA
Riboflavin biosynthesis protein RibBA {ECO:0000255|HAMAP-Rule:MF_01283}; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 0.999
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.998
ribH
6,7-dimethyl-8-ribityllumazine synthase {ECO:0000255|HAMAP-Rule:MF_00178}; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.998
ribC
Riboflavin biosynthesis protein RibC; sp|P54575|RIBC_BACSU;evalue=3e-042; PctID=35.02; score=172; Belongs to the ribF family.
  
 
 0.928
ydgI
Putative NAD(P)H nitroreductase YdgI; sp|P96707|YDGI_BACSU;evalue=2e-009; PctID=43.75; score=62.4.
       0.796
hisI
Histidine biosynthesis bifunctional protein HisIE {ECO:0000255|HAMAP-Rule:MF_01019}; sp|Q8A7Z7|HIS2_BACTN;evalue=9e-055; PctID=55.10; score=213; In the N-terminal section; belongs to the PRA-CH family.
  
    0.719
dapA-2
4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000255|HAMAP-Rule:MF_00418}; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.698
rpmE2
50S ribosomal protein L31 type B {ECO:0000255|HAMAP-Rule:MF_00502}; sp|A6LDB6|RL31B_PARD8;evalue=3e-037; PctID=85.71; score=153.
   
    0.635
SCM59282.1
Putative protein {ECO:0000313|EMBL:CEA17133,1}; tr|A0A098C3Z4|A0A098C3Z4_9PORP;evalue=1e-155; PctID=58.74; score=556.
       0.470
hisC
Histidinol-phosphate aminotransferase {ECO:0000255|HAMAP-Rule:MF_01023}; sp|A5FFY0|HIS8_FLAJ1;evalue=9e-086; PctID=47.84; score=317; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.403
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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