node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acsm3 | PRODH | ING2E5A_2319 | ING2E5A_1052 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | 0.576 |
Acsm3 | SCM55721.1 | ING2E5A_2319 | ING2E5A_0532 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.575 |
Acsm3 | SCM56797.1 | ING2E5A_2319 | ING2E5A_1050 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity). L-glutamate + NADH. glutamate; L-glutamate from L-proline: step 2/2; sp|Q54RA2|AL4A1_DICDI;evalue=8e-151; PctID=49.08; score=534. | 0.672 |
Acsm3 | SCM58349.1 | ING2E5A_2319 | ING2E5A_1770 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9Y289|SC5A6_HUMAN;evalue=6e-019; PctID=28.75; score=95.9; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.575 |
Acsm3 | SCM59418.1 | ING2E5A_2319 | ING2E5A_2622 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | Putative membrane protein HI_1126,1; sp|O86233|Y112B_HAEIN;evalue=6e-036; PctID=44.16; score=152. | 0.635 |
Acsm3 | SCM59420.1 | ING2E5A_2319 | ING2E5A_2624 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | Putative protein {ECO:0000313|EMBL:EKN12730,1}; tr|K5ZN76|K5ZN76_9PORP;evalue=0.0; PctID=68.17; score=839. | 0.408 |
PRODH | Acsm3 | ING2E5A_1052 | ING2E5A_2319 | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | 0.576 |
PRODH | SCM55721.1 | ING2E5A_1052 | ING2E5A_0532 | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.704 |
PRODH | SCM56797.1 | ING2E5A_1052 | ING2E5A_1050 | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity). L-glutamate + NADH. glutamate; L-glutamate from L-proline: step 2/2; sp|Q54RA2|AL4A1_DICDI;evalue=8e-151; PctID=49.08; score=534. | 0.995 |
PRODH | SCM58349.1 | ING2E5A_1052 | ING2E5A_1770 | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9Y289|SC5A6_HUMAN;evalue=6e-019; PctID=28.75; score=95.9; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.750 |
PRODH | SCM59418.1 | ING2E5A_1052 | ING2E5A_2622 | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | Putative membrane protein HI_1126,1; sp|O86233|Y112B_HAEIN;evalue=6e-036; PctID=44.16; score=152. | 0.534 |
SCM55721.1 | Acsm3 | ING2E5A_0532 | ING2E5A_2319 | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | 0.575 |
SCM55721.1 | PRODH | ING2E5A_0532 | ING2E5A_1052 | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | 0.704 |
SCM55721.1 | SCM56797.1 | ING2E5A_0532 | ING2E5A_1050 | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity). L-glutamate + NADH. glutamate; L-glutamate from L-proline: step 2/2; sp|Q54RA2|AL4A1_DICDI;evalue=8e-151; PctID=49.08; score=534. | 0.609 |
SCM55721.1 | SCM59418.1 | ING2E5A_0532 | ING2E5A_2622 | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Putative membrane protein HI_1126,1; sp|O86233|Y112B_HAEIN;evalue=6e-036; PctID=44.16; score=152. | 0.631 |
SCM55721.1 | sstT | ING2E5A_0532 | ING2E5A_2619 | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Serine/threonine transporter SstT {ECO:0000255|HAMAP-Rule:MF_01582}; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Rule:MF_01582}; Multi-pass membrane protein (TC 2.A.23) family; sp|Q3K9V7|SSTT_PSEPF;evalue=2e-010; PctID=24.77; score=67.0; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.590 |
SCM56797.1 | Acsm3 | ING2E5A_1050 | ING2E5A_2319 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity). L-glutamate + NADH. glutamate; L-glutamate from L-proline: step 2/2; sp|Q54RA2|AL4A1_DICDI;evalue=8e-151; PctID=49.08; score=534. | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity). + an acyl-CoA. Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence=; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence=; family; sp|Q6SKG1|ACSM3_RAT;evalue=6e-122; PctID=40.59; score=438. | 0.672 |
SCM56797.1 | PRODH | ING2E5A_1050 | ING2E5A_1052 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity). L-glutamate + NADH. glutamate; L-glutamate from L-proline: step 2/2; sp|Q54RA2|AL4A1_DICDI;evalue=8e-151; PctID=49.08; score=534. | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. carboxylate + a quinol. Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence=; glutamate; L-glutamate from L-proline: step 1/2. Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O43272-4; Name=2; IsoId=O43272-2; Sequence=VSP_021848; Name=3; IsoId=O43272-1; Sequence=VSP_040848, VSP_040849; to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas. of proline metabolism resulting in elevated levels of proline in the plasma and urine. The disorder is generally benign and m [...] | 0.995 |
SCM56797.1 | SCM55721.1 | ING2E5A_1050 | ING2E5A_0532 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity). L-glutamate + NADH. glutamate; L-glutamate from L-proline: step 2/2; sp|Q54RA2|AL4A1_DICDI;evalue=8e-151; PctID=49.08; score=534. | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9XT77|SC5A6_RABIT;evalue=5e-038; PctID=27.65; score=159; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.609 |
SCM56797.1 | SCM58349.1 | ING2E5A_1050 | ING2E5A_1770 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity). L-glutamate + NADH. glutamate; L-glutamate from L-proline: step 2/2; sp|Q54RA2|AL4A1_DICDI;evalue=8e-151; PctID=49.08; score=534. | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium. (TC 2.A.21) family; sp|Q9Y289|SC5A6_HUMAN;evalue=6e-019; PctID=28.75; score=95.9; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.609 |