STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsKDNA translocase FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). similarity). membrane protein Note=Located at the septum. the localization to the septal ring and is requ [...] (836 aa)    
Predicted Functional Partners:
noc
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Rule:MF_02015}. Rule:MF_02015}; sp|A0RLQ9|NOC_BACAH,sp|B7JIK8|NOC_BACC0, sp|C1ER74|NOC_BACC3,sp|C3LGT8|NOC_BACAC, sp|C3P3F2|NOC_BACAA,sp|Q6HAF5|NOC_BACHK, sp|Q81JH5|NOC_BACAN;evalue=3e-044; PctID=45.45; score= [...]
 
  
 0.792
SCM59517.1
Putative protein {ECO:0000313|EMBL:CEA15008,1}; tr|A0A098BXX4|A0A098BXX4_9PORP;evalue=2e-049; PctID=51.58; score=201.
 
  
 0.725
SCM59371.1
Putative protein {ECO:0000313|EMBL:CEA15000,1}; tr|A0A098BWG1|A0A098BWG1_9PORP;evalue=1e-079; PctID=57.20; score=302.
  
 
 0.709
mfd
Transcription-repair-coupling factor {ECO:0000255|HAMAP-Rule:MF_00969}; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
 
   
 0.680
xerC
Tyrosine recombinase XerC {ECO:0000255|HAMAP-Rule:MF_01808}; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
   
 0.617
soj
Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of Spo0A. P05648:dnaA; NbExp=2; IntAct=EBI-2014674, EBI-2014722; chromosome partioning; sp|P37522|SOJ_BACSU;evalue=4e-069; PctID=53.09; score=261.
  
  
 0.598
dnaA
Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377}; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
  
 0.597
lrp
Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes; sp|P0A2S0|LRP_SALTY,sp|P0ACJ0|LRP_ECOLI, sp|P0ACJ1|LRP_ECOL6,sp|P0ACJ2|LRP_ECO57, sp|P0ACJ3|LRP_SHIFL,sp|P0ACJ4|LRP_ENTAE, sp|P37424|LRP_KLEPN,sp|P37425|LRP_SERMA;evalue=1e-022; PctID=37.06; score=105.
   
 0.591
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase {ECO:0000255|HAMAP-Rule:MF_00111}; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.584
xerD
Tyrosine recombinase XerD {ECO:0000255|HAMAP-Rule:MF_01807}; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
   
 0.584
Your Current Organism:
Petrimonas mucosa
NCBI taxonomy Id: 1642646
Other names: CECT 8611, DSM 28695, P. mucosa, Petrimonas mucosa Hahnke et al. 2016, Petrimonas sp. ING2-E5A, strain ING2 E5A, strain ING2-E5A
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