STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSM36_0434The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B [...] (501 aa)    
Predicted Functional Partners:
ileS
Isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
       0.556
PSM36_0777
Predicted ATPase, AAA+ superfamily [General function prediction only]; High confidence in function and specificity.
  
     0.521
PSM36_0779
Predicted transcriptional regulator, contains HTH domain [Transcription]; High confidence in function and specificity.
  
    0.500
PSM36_1407
Hypothetical protein.
  
     0.498
PSM36_2704
Putative transcriptional regulator; High confidence in function and specificity.
  
    0.474
PSM36_1621
Hypothetical protein.
  
    0.469
PSM36_0436
DnaK suppressor protein; RNA polymerase-binding transcription factor DksA [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity.
       0.450
PSM36_3083
Predicted ATPase, AAA+ superfamily [General function prediction only]; High confidence in function and specificity.
  
     0.444
PSM36_2703
Hypothetical protein; Family membership.
  
    0.413
Your Current Organism:
Proteiniphilum saccharofermentans
NCBI taxonomy Id: 1642647
Other names: CECT 8610, DSM 28694, LMG 28299, LMG:28299, P. saccharofermentans, Proteiniphilum saccharofermentans Hahnke et al. 2016, Proteiniphilum sp. M3/6, strain M3/6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.